A CHIRAL N-CROTONYLOXAZOLIDINONE DIELS-ALDER ADDUCT

被引：3

作者：

MARSH, RE ^{[1
]}

SCHAEFER, WP ^{[1
]}

KUKKOLA, PJ ^{[1
]}

MYERS, AG ^{[1
]}

机构：

[1] CALTECH,BECKMAN INST,PASADENA,CA 91125

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1992年 / 48卷

关键词：

D O I：

10.1107/S0108270192000738

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(4S)-4-Benzyl-3-[(4S,5S)-(1-methoxy-5-methylcyclohexen-4-yl)carbonyl]-2-oxazolidinone, C19H23NO4, M(r) = 329.40, monoclinic, P2(1), a = 11.453 (3), b = 7.163 (4), c = 11.929 (2) angstrom, beta = 111.86 (2)-degrees, V = 908.3 (5) angstrom3, Z = 2, D(x) = 1.20 g cm-3, lambda(Mo Kalpha) = 0.71073 angstrom, mu = 0.79 cm-1, F(000) = 352, T = 297 K, R = 0.034 for 885 reflections with F(o)2 > 0. The molecule is extended in the crystal; there is a small twist, -13.1 (2)-degrees, about the amide-like C-N bond joining the oxazolidinone ring to the carbonyl group. The configurations at the two optical centers in the cyclohexene ring confirm the anticipated stereospecificity of the Diels-Alder cycloaddition synthesis.

引用

页码：1622 / 1624

页数：3

共 13 条

[1] METAL-ASSISTED ALDOL CONDENSATION OF CHIRAL ALPHA-HALOGENATED IMIDE ENOLATES - A STEREOCONTROLLED CHIRAL EPOXIDE SYNTHESIS [J].