ISATOGENS .6. SYNTHESIS OF ISATOGENS VIA TOLAN (DIPHENYLACETYLENE) INTERMEDIATES

被引:55
作者
BOND, CC
HOOPER, M
机构
[1] School of Pharmacy, The Polytechnic, Sunderland, Co. Durham
来源
JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1969年 / 18期
关键词
D O I
10.1039/j39690002453
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A number of substituted 2-nitrotolans and isatogens have been prepared in high yield from copper(I) 2-nitrophenylacetylide and substituted aromatic iodo-compounds. The reaction has been shown to be affected by both electronic and steric factors and its limitations are discussed. 2-Carbamoyltolans have been shown to cyclise to aminoindenones. A number of novel compounds have been isolated from these reactions and their significance, with regard to the mechanism of the reaction between isatogens and substituted acetylenes, is discussed. The influence of different solvents on the course of the latter reaction is reported.
引用
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页码:2453 / +
页数:1
相关论文
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