PREPARATION AND BIOCHEMICAL-PROPERTIES OF PGH3

被引：43

作者：

SMITH, DR

WEATHERLY, BC

SALMON, JA

UBATUBA, FB

GRYGLEWSKI, RJ

MONCADA, S

机构：

[1] Wellcome Research Laboratories, Beckenham, Kent BR3 3BS, Langley Court

来源：

PROSTAGLANDINS & OTHER LIPID MEDIATORS | 1979年 / 18卷 / 03期

关键词：

D O I：

10.1016/S0090-6980(79)80061-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

PGH3 was biosynthesised from all-cis-5,8,11,14,17-eicosapentaenoic acid (20:5ω3) by an acetone-pentane powder of ram seminal vesicles and its structure was confirmed by GLC-MS after its reduction to PGF3α. PGH3 was transformed by horse platelet microsomes to TXB3, and by aortic microsomes to Δ17-6-keto-PGF1α. The structures of these compounds were confirmed by GLC-MS. © 1979.

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页码：423 / 438

页数：16

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