APPLICATION OF IMMUNOSTAINING FOR MUSCLE-SPECIFIC ACTIN IN DETECTION OF MYOEPITHELIAL CELLS IN BREAST FINE-NEEDLE ASPIRATES

被引：15

作者：

MASOOD, S

LU, L

ASSAFMUNASIFI, MN

MCCAULLEY, K

机构：

[1] Department of Pathology, University of Florida Health Science Center, Jacksonville, Florida, Jacksonville

来源：

DIAGNOSTIC CYTOPATHOLOGY | 1995年 / 13卷 / 01期

关键词：

MUSCLE SPECIFIC ACTIN; MYOEPITHELIAL CELLS; BREAST FINE-NEEDLE ASPIRATES;

D O I：

10.1002/dc.2840130115

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Myoepithelial cells play an important role in the interpretation of breast fine-needle aspiration biopsy, since these cells are believed to be a component of a benign process in breast lesions. Myoepithelial cells are usually easy to recognize, however, other cells can morphologically simulate myoepithelial cells and make the distinction difficult. To assess the feasibility of immunostaining as an adjunct to identify myoepithelial cells, we have used immunocytochemistry using monoclonal antibody against muscle specific actin (MSA) in our breast fine-needle aspirates. Herein, we report our experience in immunocytochemical detection of myoepithelial cells using labeled Streptavidin Biotin Detection System on destained Papanicolaou stained smears and cell block preparations obtained from breast aspirates. (C) 1995 Wiley-Liss, Inc.

引用

页码：71 / 74

页数：4

共 23 条

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