FRAGMENTS OF THE INTERNAL TRANSCRIBED SPACER-1 OF PRE-RIBOSOMAL-RNA ACCUMULATE IN SACCHAROMYCES-CEREVISIAE LACKING 5'-]3' EXORIBONUCLEASE-1

被引：106

作者：

STEVENS, A

HSU, CL

ISHAM, KR

LARIMER, FW

机构：

来源：

JOURNAL OF BACTERIOLOGY | 1991年 / 173卷 / 21期

关键词：

D O I：

10.1128/jb.173.21.7024-7028.1991

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The portion of the internal transcribed spacer 1 found on 20S pre-rRNA accumulates in Saccharomyces cerevisiae lacking 5' --> 3' exoribonuclease 1, showing that an endonucleolytic cleavage at the 3' terminus of 18S rRNA is involved in the 20S pre-rRNA to 18S mature rRNA conversion. Smaller fragments of the spacer sequence are also found. The exoribonuclease may be involved as a cytoplasmic RNase in the hydrolysis of the spacer.

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页码：7024 / 7028

页数：5

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