OBSERVATIONS REGARDING ESCHENMOSER SULFIDE CONTRACTIONS OF BETA-OXYGENATED THIOLACTAMS

被引：12

作者：

HART, DJ ^{[1
]}

SUN, LQ ^{[1
]}

KOZIKOWSKI, AP ^{[1
]}

机构：

[1] GEORGETOWN UNIV,SCH MED,WASHINGTON,DC 20007

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 43期

关键词：

D O I：

10.1016/0040-4039(95)01648-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Application of an Eschenmoser sulfide contraction to a thiolactam bearing a beta-acyloxy group was complicated by a competitive beta-elimination reaction. Changing the beta-substituent to an alkoxy group retarded the rate of elimination such that sulfide contraction products could be obtained.

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页码：7787 / 7790

页数：4

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