SYNTHESIS OF1-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-18-(2,6,6-TRI8ETHYL-2-CYCLOHEXEN-1-YLIDENE)-3,7,12,16-TETRAMETHYL-2,4,6,8,10,12,14,16,18-OCTADECANONAENE AND ITS REARRANGEMENT TO TRANS-BETA-CAROTENE

被引：9

作者：

SURMATIS, JD

GIBAS, J

THOMMEN, R

机构：

[1] Technical Development Department, Hoffmann-La Roche, Inc., Nutley, New Jersey

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1969年 / 34卷 / 10期

关键词：

D O I：

10.1021/jo01262a054

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel synthesis of 1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-18-(2,6,6-trimethyl-2-cyclohexen-1-ylidene)-3,7,12,-16-tetramethyl-2,4,6,8,10,12,14,16,18-octad canonaene (6) and itsrearrangement to trans-β-carotene arereported. A new type of carotenoid with a cross-conjugated keto function (4) was used asan intermediate for the synthesis of 6. © 1969, American Chemical Society. All rights reserved.

引用

页码：3039 / +

页数：1

共 6 条

[1] BIOLOGICAL ASSAY OF VITAMIN-A - LIVER STORAGE TEST OF GUGGENHEIM AND KOCH [J].