APOVLDLII GENE-TRANSCRIPTION IN IMMATURE COCKERELS WITHOUT ESTRADIOL STIMULATION

1. 1. Previous studies have led to the conclusion that the gene encoding the apo very low density lipoprotein II (ApoVLDLII) is under full estrogen control. However, by using a sensitive hybridization technique we found a weak expression of this gene in some males in the absence of hormone. 2. 2. As the vitellogenin II gene, which is also estrogen dependant, remains inactive in these animals it is likely that they carry a deregulated allele of the ApoVLDII gene. 3. 3. The highest level of ApoVLDLII mRNA is found in genetically fat males suggesting a possible involvement of the ApoVLDLII gene in fatness determinism. © 1990.