MONOCLONAL-ANTIBODIES TO KUNJIN AND KOKOBERA VIRUSES

被引：38

作者：

HALL, RA

BURGESS, GW

KAY, BH

CLANCY, P

机构：

[1] QUEENSLAND INST MED RES,HERSTON,QLD 4006,AUSTRALIA

[2] GRAD SCH TROP VET SCI,TOWNSVILLE,QLD 4811,AUSTRALIA

来源：

IMMUNOLOGY AND CELL BIOLOGY | 1991年 / 69卷

关键词：

D O I：

10.1038/icb.1991.7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Five monoclonal antibodies (MoAb) were produced to the envelope (E) protein of Kunjin (KUN) virus. Three of these were specific for the KUN/West Nile complex, and two reacted with epitopes that were common to the flavivirus family. These MoAb defined at least four distinct epitopes on the E protein of KUN virus. Eight MoAb were also produced to unidentified proteins of Kokobera (KOK) virus. Seven were specific for KOK, while the remaining antibody cross-reacted with Stratford virus and an unregistered flavivirus CS946. The application of these MoAb to arboviral surveillance is discussed.

引用

页码：47 / 49

页数：3

共 8 条

[1] ILLNESS CAUSED BY A KOKOBERA-LIKE VIRUS IN SOUTHEASTERN AUSTRALIA [J].