THE INFLUENCE OF CALORIE SOURCE ON WATER AND SODIUM BALANCES DURING INTRAVENOUS REFEEDING OF MALNOURISHED RABBITS

被引:8
作者
FRANCH, G [1 ]
GUIRAO, X [1 ]
GARCIADOMINGO, M [1 ]
GIL, MJ [1 ]
SALAS, E [1 ]
SITGESSERRA, A [1 ]
机构
[1] UNIV AUTONOMA BARCELONA,HOSP UNIV MAR,DEPT SURG,P MARITIM 25-29,E-08003 BARCELONA,SPAIN
关键词
D O I
10.1016/0261-5614(92)90067-Z
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
34 New Zealand rabbits were starved until a mean weight loss of 15% to 20% was achieved and then were parenterally re-fed with four different total parenteral nutrition (TPN) formulae for 6 days. Regimens were isocaloric (85 kcal/kg/day) and isonitrogenous (0.52 gN/kg/day) with the following formulae: group S-GLU-70 (water 100 ml/kg/day, Na 7 mEq/day and 70/30% of calories as glucose/lipids, n = 9), group S-GLU-50 (water 100 ml/kg/day, Na 7 mEq/day and 50/50% of calories as glucose/lipids, n = 9), group L-GLU-30 (water 70 ml/kg/day, no sodium and 30/70% of calories as glucose/lipids, n = 8) and group L-GLU-50 (water 70 ml/kg/day, no sodium and 50/50% of calories as glucose/lipids, n = 8). The group S-GLU-70 showed the highest water and sodium balances (p = 0.001 respectively, ANOVA test). Group S-GLU-70 showed also a greater weight gain (p = 0.0001) and, although not statistically significant, the lowest albumin at the end of the TPN. Glucose load appears to be responsible for the rapid weight gain and positive water and sodium balances during TPN in depleted non-stressed animals.
引用
收藏
页码:59 / 61
页数:3
相关论文
共 10 条
  • [1] Buzby, Mullen, Matthews, Hobbs, Rosato, Prognostic nutritional index in gastrointestinal surgery, American Journal of Surgery, 139, pp. 160-167, (1980)
  • [2] Starker, Lasala, Askanazi, Gump, Forse, Kinney, The response to TPN. A form of nutritonal assessment, Annals of Surgery, 198, pp. 720-724, (1983)
  • [3] Gamble, Physiological information gained from studies on life raft ration, Harvey lectures, 42, pp. 247-273, (1947)
  • [4] Committee of Animal Nutrition, Nutrient requirements of rabbits, (1977)
  • [5] Elwyn, Bryan-Brown, Shoemaker, Nutritional aspects of body water dislocation in postoperative and depleted patients, Annals of Surgery, 182, pp. 76-85, (1975)
  • [6] Klahr, Alleyne, Effects of chronic protein-calorie malnutrition on the kidney, Kidney International, 3, pp. 129-141, (1973)
  • [7] MacFie, Smith, Hill, Glucose or fat as a nonprotein energy source? A controlled trial in gastroenterological patients requiring intravenous nutrition, Gastroenterology, 80, pp. 103-107, (1981)
  • [8] Starker, Gump, Askanazi, Et al., Serum albumin levels as an index of nutrition support, Surgery, 91, pp. 194-199, (1982)
  • [9] Forse, Shizgal, The assessment of malnutrition, Surgery, 88, pp. 17-24, (1980)
  • [10] Sitges-Serra, Gil, Martinez-Rodenas, The influence of TPN formulation on the metabolic response to preoperative refeeding in depleted patients, British Journal Clinical Practice, 42, pp. 133-137, (1988)