HYPOLIPEMIC ACTIVITY IN RATS OF BERGENIN, THE MAJOR CONSTITUENT OF FLUEGGEA-MICROCARPA

被引：37

作者：

JAHROMI, MAF

CHANSOURIA, JPN

RAY, AB

机构：

[1] BANARAS HINDU UNIV,DEPT MED CHEM,VARANASI 221005,UTTAR PRADESH,INDIA

[2] BANARAS HINDU UNIV,INST MED SCI,CTR EXPTL MED & SURG,VARANASI 221005,UTTAR PRADESH,INDIA

来源：

PHYTOTHERAPY RESEARCH | 1992年 / 6卷 / 04期

关键词：

FLUEGGEA-MICROCARPA BLUME; BERGENIN; LIPID-LOWERING ACTIVITY; ATHEROGENIC INDEX;

D O I：

10.1002/ptr.2650060403

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Oral administration of bergenin, isolated from the leaves of Flueggea microcarpa, to hyperlipidaemic rats for 14 days significantly decreased serum total lipid without much change in serum cholesterol and triglycerides. However, after 21 days of administration, the serum cholesterol, triglycerides, low-density lipoprotein (LDL)- and very low-density lipoprotein (VLDL)-cholesterol levels were significantly reduced while the serum high-density lipoprotein (HDL)-cholesterol level was elevated. Bergenin-treated animals also showed a significant decrease in atherogenic index.

引用

页码：180 / 183

页数：4

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