COMPARISON OF DISKUS(TM) INHALER, A NEW MULTIDOSE POWDER INHALER, WITH DISKHALER(TM) INHALER FOR THE DELIVERY OF SALMETEROL TO ASTHMATIC-PATIENTS

被引：39

作者：

BOULET, LP

COWIE, R

JOHNSTON, P

KRAKOVSKY, D

MARK, S

机构：

[1] Hôpital Laval Sainte-Foy, Quebec and Université Laval, Mississauga, ON

[2] Department of Medicine, University of Calgary, Mississauga, ON

[3] Glaxo Wellcome Inc., Mississauga, ON

来源：

JOURNAL OF ASTHMA | 1995年 / 32卷 / 06期

关键词：

D O I：

10.3109/02770909409077754

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Administration of the long-acting beta(2)-adrenoceptor agonist salmeterol from a new, easy-to-operate, multidose powder inhaler (Diskus(TM)) containing 60 sealed doses in a foil strip has been compared with administration from a Diskhaler(TM) inhaler in a multicenter, double-blind, double-dummy, parallel-group study. Asthmatic patients taking anti-inflammatory treatment, with baseline FEV(1) greater than or equal to 60% less than or equal to 90% predicted were treated for 4 weeks with salmeterol 50 mu g twice daily from either the Diskus or Diskhaler inhaler. The two treatments were equivalent (90% CLs for the difference in mean morning PEFR: -2.2, 8.7 L/min). The Diskus inhaler was rated easier to use and was preferred by more patients than the Diskhaler inhaler (73% vs. 15%).

引用

页码：429 / 436

页数：8

共 13 条

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