ELECTROPHYSIOLOGICAL EVIDENCE FOR OXYTOCIN RECEPTORS ON SYMPATHETIC PREGANGLIONIC NEURONS - AN IN-VITRO STUDY ON THE NEONATAL RAT

被引：28

作者：

DESAULLES, E

REITER, MK

FELTZ, P

机构：

[1] Laboratoire de Physiologie Générale, URA CNRS 1446, 67084 Strasbourg

来源：

BRAIN RESEARCH | 1995年 / 699卷 / 01期

关键词：

SYMPATHETIC PREGANGLIONIC NEURON; OXYTOCIN RECEPTOR; SPINAL CORD; SLICE; IN VITRO; AUTONOMIC NERVOUS SYSTEM; INTRACELLULAR RECORDING; BIOCYTIN;

D O I：

10.1016/0006-8993(95)01019-R

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

The action of oxytocin (0.01-1 mu M) on sympathetic preganglionic neurones was studied by intracellular recording in slices of neonatal rat thoracic spinal cord. In 85% of the cells superfusion induced a slow tetrodotoxin-insensitive depolarization accompanied by the appearance or increase in frequency of repetitive discharges. Oxytocin also caused some cells to switch from silent neurones to spontaneously active ones. These effects were reversibly blocked by a specific oxytocin antagonist.

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页码：139 / 142

页数：4

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