REDUCTION AND SUBSEQUENT OXIDATION OF A CYTOCHROME-B OF HUMAN-NEUTROPHILS AFTER STIMULATION WITH PHORBOL-MYRISTATE ACETATE

被引：79

作者：

SEGAL, AW ^{[1
]}

JONES, OTG ^{[1
]}

机构：

[1] UNIV BRISTOL,DEPT BIOCHEM,BRISTOL BS8 1TH,AVON,ENGLAND

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 88卷 / 01期

关键词：

D O I：

10.1016/0006-291X(79)91706-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Difference spectroscopy of human neutrophils stimulated with phorbol myristate acetate as compared with unstimulated cells produced the characteristic spectral changes of the reduced cytochrome that has recently been described in these cells. The reduction of this cytochrome b is enhanced under anaerobic conditions and is partially reversed upon the reintroduction of air. This reversible oxidation and reduction after stimulation with phorbol myristate provides additional evidence for the role of this cytochrome b as a component of the microbicidal oxidase system. © 1979.

引用

页码：130 / 134

页数：5

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