EFFECTS OF EIMERIA-LABBEANA AND E-STIEDAI INFECTION ON THE ACTIVITY OF SOME ENZYMES IN THE SERUM AND LIVER OF THEIR HOSTS

Glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), alkaline phosphatase and acid phosphatase activities were measured in the serum and liver of both normal and Eimeria-infected palm doves and rabbits. No significant increase in GOT activity was noticed in the serum of infected male or female palm doves. In contrast, GOT activity decreased insignificantly in the liver of both sexes of infected birds. On the other hand inoculated rabbits showed a significant increase in the serum GOT activity of both sexes. In the liver, however, a non-significant increase in GOT activity was obtained in males and a non-significant decrease, in females subsequent to infection. Serum GPT activity whowed a highly significant increase in infected male doves and a significant increase in females; liver GPT activity decreased non-significantly in both sexes. Infected rabbits showed a non-significant increase in GPT activity in the serum and liver of both males and females. The activity of alkaline phosphatase in infected male palm doves was found to increase significantly in serum and highly significantly in liver. In contrast, enzyme activity in both the serum and the liver of female doves was found to decrease insignificantly after infection. In infected male and female rabbits, the activity of serum alkaline phosphatase increased non-significantly, whereas liver alkaline phosphatase activity decreased significantly in male animals and non-significantly in female rabbits. Acid phosphatase activity showed a highly significant decrease in both the serum and the liver of infected male palm doves; on the other hand, it increased non-significantly in both the serum and the liver of infected females. Eimeria infection of rabbits increased serum acid phosphatase non-significantly in both sexes. In contrast, enzyme activity in the liver decreased highly significantly in males and non-significantly in females. The general increase noticed in enzyme activity, especially that of GPT (due to infection), may be attributable to cell damage, which in turn leads to leakage of the exzyme. An inverse response of the palm dove (bird) and the rabbit (mammalian) to infection with the corresponding Eimeria species was also observed. © 1990 Springer-Verlag.