ION-BEAM INDUCED DAMAGE AND ELEMENT LOSS DURING A MICROANALYSIS OF BIOLOGICAL TISSUE

被引：26

作者：

KIRBY, BJ ^{[1
]}

LEGGE, GJF ^{[1
]}

机构：

[1] UNIV MELBOURNE,SCH PHYS,MICROANALYT RES CTR,PARKVILLE,VIC 3052,AUSTRALIA

来源：

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS | 1991年 / 54卷 / 1-3期

关键词：

D O I：

10.1016/0168-583X(91)95498-3

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

Specimen damage and element loss induced by 3 MeV proton and 2 MeV alpha particle bombardment of thin sections of freeze-dried kidney tissue and embedding medium have been studied. Yields of ions scattered from H and C, and characteristic X-rays were measured versus accumulated charge, for current densities in the range from 8 x 10(-15) to 1.1 x 10(-11) A/mu-m2. Structural damage, discolouration and loss of S, Cl, C and H have been observed. Implications of this study for ion beam microanalysis of biological tissues are discussed with particular reference to the results for H loss.

引用

页码：98 / 100

页数：3