TORULOPSIS-GLABRATA FUNGEMIA - CLINICAL-FEATURES AND ANTIBODY-RESPONSES

被引：5

作者：

MATTHEWS, RC

LEE, W

DONOHOE, MS

DAMANI, NN

BURNIE, JP

机构：

[1] Department of Medical Microbiology, University of Manchester Medical School, Manchester, M13 9PT England, Oxford Road

来源：

SERODIAGNOSIS AND IMMUNOTHERAPY IN INFECTIOUS DISEASE | 1990年 / 4卷 / 03期

关键词：

55 kDa immunodominant antigen; immunoblotting; Torulopsis glabrata;

D O I：

10.1016/0888-0786(90)90006-A

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Sera from 16 cases of T. glabrata infection were examined for antibody by immunoblotting against T. glabrata NCPF 3240. This revealed a key immunodominant antigen of 55 kDa which was conserved within the species. Antibody against this occurred in 11 of the 13 cases who survived. Two cases recovered without antibody production. The overall mortality of treated infection was 19%. Reverse passive latex agglutination for antigen was negative in 62·5% of cases. Infection produced no typical clinical picture and was associated with ketoconazole prophylaxis in 62·5% of patients. © 1990.

引用

页码：209 / 216

页数：8

共 14 条

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