ENZYME-ENZYME INTERACTIONS AND THEIR METABOLIC ROLE

被引：91

作者：

SRERE, PA

OVADI, J

机构：

[1] UNIV TEXAS, SW MED CTR, DALLAS, TX 75230 USA

[2] HUNGARIAN ACAD SCI, BIOL RES CTR, INST ENZYMOL, H-1518 BUDAPEST, HUNGARY

来源：

FEBS LETTERS | 1990年 / 268卷 / 02期

关键词：

Channeling; Enzyme-enzyme interaction; Metabolic complex: Metabolic control theory;

D O I：

10.1016/0014-5793(90)81286-W

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

There are continuing reports on the existence of complexes of sequential metabolic enzymes. New techniques for their detection have been described and include affinity electrophoresis and the use of anti-idiotypic antibodies. Channeling of substrates has been reported for several systems as well as direct substrate transfer through dynamic enzyme associations. Kinetic parameters of metabolic control of organized systems have been formulated and tested in several systems. These recent results are expanding our understanding of metabolic processes and their control. © 1990.

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页码：360 / 364

页数：5

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