THE SYNTHESIS OF 1,6-DISUBSTITUTED INDANES WHICH MIMIC THE ORIENTATION OF AMINO-ACID SIDE-CHAINS IN A PROTEIN ALPHA-HELIX MOTIF

被引：32

作者：

NOLAN, WP ^{[1
]}

RATCLIFFE, GS ^{[1
]}

REES, DC ^{[1
]}

机构：

[1] PARKE DAVIS NEUROSCI RES CTR,ADDENBROOKES HOSP SITE,HILLS RD,CAMBRIDGE CB2 2QB,ENGLAND

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 45期

关键词：

D O I：

10.1016/S0040-4039(00)61800-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We utilize a 1,6-disubstituted indane as a template onto which two amino acid side-chains are appended in an orientation which mimics that found in a protein alpha-helix motif.

引用

页码：6879 / 6882

页数：4

共 13 条

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