DUAL LOCALIZATION OF THE MITOCHONDRIAL PHOSPHOLIPASE-A2 - OUTER-MEMBRANE CONTACT SITES AND INNER MEMBRANE

被引：21

作者：

LEVRAT, C ^{[1
]}

LOUISOT, P ^{[1
]}

机构：

[1] LYON S MED SCH,DEPT GEN & MED BIOCHEM,CNRS,U189,INSERM,BP 12,F-69921 OULLINS,FRANCE

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1992年 / 183卷 / 02期

关键词：

D O I：

10.1016/0006-291X(92)90542-S

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mitochondria were fractionated according to a procedure which allowed to get free outer and inner membrane plus two distinct contact sites between the two membranes. The data indicate that phospholipase A2 is localized in outer membrane contact sites and in inner membrane. The enzyme activity is twice higher in the contact site fraction than in the free membrane. The major fatty acids released are linoleic and docosahexanoic acids. © 1992.

引用

页码：719 / 724

页数：6

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