PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE-LIKE IMMUNOREACTIVITY IN AUTONOMIC REGULATORY AREAS OF THE RAT MEDULLA-OBLONGATA

被引：74

作者：

LEGRADI, G

SHIODA, S

ARIMURA, A

机构：

[1] U.S.-Japan Biomedical Research Laboratories, Tulane University Hebert Center, Belle Chasse, LA 70037

来源：

NEUROSCIENCE LETTERS | 1994年 / 176卷 / 02期

关键词：

PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RAT; IMMUNOHISTOCHEMISTRY; SOLITARY NUCLEUS; VENTROLATERAL MEDULLA; NUCLEUS AMBIGUUS; AUTONOMIC FUNCTION;

D O I：

10.1016/0304-3940(94)90080-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Pituitary adenylate cyclase-activating polypeptide-like immunoreactivity (PACAP-LI) was mapped immunohistochemically in the rat medulla oblongata. We found the majority of perikarya with PACAP-LI in the visceral areas of the solitary nucleus, dorsal motor vagal nucleus, nucleus ambiguus, ventrolateral medulla, ventral medullary surface, and caudal raphe nuclei. Medium densities of labeled fibers were detected in the area postrema, solitary nucleus, dorsal vagal and raphe pallidus nuclei. Our morphological data support the hypothesis that PACAP is a central regulator of visceral functions.

引用

页码：193 / 196

页数：4

共 17 条

[1]

AKARCA US, 1993, AM J GASTROENTEROL, V33, P1502

[2] TISSUE DISTRIBUTION OF PACAP AS DETERMINED BY RIA - HIGHLY ABUNDANT IN THE RAT-BRAIN AND TESTES [J].