NUCLEOTIDE EXCISION-REPAIR AND THE LINK WITH TRANSCRIPTION

被引：139

作者：

LEHMANN, AR

机构：

[1] MRC Cell Mutation Unit, University of Sussex, Brighton, BN1 9RR, Faimer

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1995年 / 20卷 / 10期

关键词：

D O I：

10.1016/S0968-0004(00)89088-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nucleotide excision repair (NER) uses the products of about 30 genes to remove a damage-containing oligonucleotide from cellular DNA. The transcription factor TFIIH is an essential component of NER, in man, defects in NER can result in three distinct genetic disorders, whose features can be ascribed to abnormalities in DNA repair or transcription.

引用

页码：402 / 405

页数：4

共 29 条

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