THE DISTRIBUTION OF 5-METHYLCYTOSINE IN THE NUCLEAR GENOME OF PLANTS

被引：48

作者：

MONTERO, LM ^{[1
]}

FILIPSKI, J ^{[1
]}

GIL, P ^{[1
]}

CAPEL, J ^{[1
]}

MARTINEZZAPATER, JM ^{[1
]}

SALINAS, J ^{[1
]}

机构：

[1] INST J MONOD,CNRS,F-75005 PARIS,FRANCE

来源：

NUCLEIC ACIDS RESEARCH | 1992年 / 20卷 / 12期

关键词：

D O I：

10.1093/nar/20.12.3207

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have determined the 5-methylcytosine (5mC) content in high molecular weight DNA, from two dicot (tobacco and pea) and two monocot (wheat and maize) plant species, fractionated according to base composition. The results show that the proportion of 5mC in the genomic fractions increases linearly with their guanine + cytosine (G + C) content while the proportion of non-methylated cytosine remains almost constant. This can be interpreted as a consequence of a difference in mutation pressure related to spontaneous deamination of 5mC to thymine between the different compartments of plant genomes.

引用

页码：3207 / 3210

页数：4

共 20 条

[1] DNA METHYLATION - THE EFFECT OF MINOR BASES ON DNA PROTEIN INTERACTIONS [J].