MEASUREMENT OF THE NASAL MUCOCILIARITY CLEARANCE BY A MODIFIED SACCHARIN METHOD

To measure the complex nasal clearance we propose to perform our variation of the Andersen saccharin method as a saccharin liquid test (SLT). The application of 3 molar aqueous sodium saccharin solutions with a Wiretrol capillary on the concha nasalis inferior or media allows simple handling, exact dosage, minimal nasal irritation and an increase in reproducibility. Application of 1 microlitre is sufficient to carry out the test. In the present study 48 healthy volunteers without any nose disease or history of sinusitis showed a saccharin transport rate of 10.4 (SD 4.2) minutes.