BIOLOGICALLY-SIGNIFICANT SCAVENGING OF THE MYELOPEROXIDASE-DERIVED OXIDANT HYPOCHLOROUS ACID BY SOME ANTIINFLAMMATORY DRUGS

被引：80

作者：

WASIL, M

HALLIWELL, B

MOORHOUSE, CP

HUTCHISON, DCS

BAUM, H

机构：

[1] KINGS COLL, SCH MED & DENT, DEPT THORAC MED, LONDON SE5 8RX, ENGLAND

[2] KINGS COLL, DEPT BIOCHEM, LONDON W8 7AH, ENGLAND

来源：

BIOCHEMICAL PHARMACOLOGY | 1987年 / 36卷 / 22期

关键词：

D O I：

10.1016/0006-2952(87)90448-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：3847 / 3850

页数：4

共 34 条

[1] BIOLOGICAL REACTIVITY OF HYPOCHLOROUS ACID - IMPLICATIONS FOR MICROBICIDAL MECHANISMS OF LEUKOCYTE MYELOPEROXIDASE [J].

ALBRICH, JM ;

MCCARTHY, CA ;

HURST, JK .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (01) :210-214

[2] OXYGEN-DEPENDENT MICROBIAL KILLING BY PHAGOCYTES .1. [J].

BABIOR, BM .

NEW ENGLAND JOURNAL OF MEDICINE, 1978, 298 (12) :659-668

[3] SUPEROXIDE PRODUCTION BY POLYMORPHONUCLEAR LEUKOCYTES IN RHEUMATOID-ARTHRITIS AND OSTEOARTHRITIS - INVIVO INHIBITION BY THE ANTIRHEUMATIC DRUG PIROXICAM DUE TO INTERFERENCE WITH THE ACTIVATION OF THE NADPH-OXIDASE [J].

BIEMOND, P ;

SWAAK, AJG ;

PENDERS, JMA ;

BEINDORFF, CM ;

KOSTER, JF .

ANNALS OF THE RHEUMATIC DISEASES, 1986, 45 (03) :249-255

[4]

CLARK RA, 1985, BLOOD, V65, P375

[5] THE EFFECT OF D-PENICILLAMINE ON HUMAN MYELOPEROXIDASE, A MECHANISM FOR THE EFFICACY OF THE DRUG IN RHEUMATOID-ARTHRITIS [J].

CUPERUS, RA ;

MUIJSERS, AO ;

WEVER, R .

BIOCHIMICA ET BIOPHYSICA ACTA, 1983, 749 (01) :18-23

[6] ANTIARTHRITIC DRUGS CONTAINING THIOL-GROUPS SCAVENGE HYPOCHLORITE AND INHIBIT ITS FORMATION BY MYELOPEROXIDASE FROM HUMAN-LEUKOCYTES - A THERAPEUTIC MECHANISM OF THESE DRUGS IN RHEUMATOID-ARTHRITIS [J].

CUPERUS, RA ;

MUIJSERS, AO ;

WEVER, R .

ARTHRITIS AND RHEUMATISM, 1985, 28 (11) :1228-1233

[7] UPTAKE OF CHLOROQUINE AND HYDROXYCHLOROQUINE BY HUMAN-BLOOD LEUKOCYTES INVITRO - RELATION TO CELLULAR CONCENTRATIONS DURING ANTIRHEUMATIC THERAPY [J].

FRENCH, JK ;

HURST, NP ;

ODONNELL, ML ;

BETTS, WH .

ANNALS OF THE RHEUMATIC DISEASES, 1987, 46 (01) :42-45

[8] MYELOPEROXIDASE OXIDATION OF SULFUR-CENTERED AND BENZOIC-ACID HYDROXYL RADICAL SCAVENGERS [J].

GREEN, TR ;

FELLMAN, JH ;

EICHER, AL .

FEBS LETTERS, 1985, 192 (01) :33-36

[9] AROMATIC HYDROXYLATION AS A POTENTIAL MEASURE OF HYDROXYL-RADICAL FORMATION INVIVO - IDENTIFICATION OF HYDROXYLATED DERIVATIVES OF SALICYLATE IN HUMAN-BODY FLUIDS [J].

GROOTVELD, M ;

HALLIWELL, B .

BIOCHEMICAL JOURNAL, 1986, 237 (02) :499-504

[10]

Grootveld M, 1987, Free Radic Res Commun, V4, P69, DOI 10.3109/10715768709088090

← 1 2 3 4 →