MODELING AND SIMULATION OF CELLULASE ADSORPTION AND RECYCLING DURING ENZYMATIC-HYDROLYSIS OF CELLULOSIC MATERIALS

Characteristics of cellulase adsorption on cellulosic substrates and their recycling during the hydrolysis of cellulose were studied. On the basis of the experimental data, a comprehensive model was set up comprising of sub-models for the enzyme adsorption, enzymatic hydrolysis and recycling of enzymes. The model equations consist of non-linear systems of ordinary differential and algebraic equations. The model parameters were identified by means of the experimental results of Singh et al. [1] and Bader et al. [2]. The simulation results with the model corresponded well with the experimental data. Thus, the good agreement between simulated and measured process variables indicates that the model is suitable for description of cellulase adsorption and recycling during hydrolysis of cellulosic substrates.