THE ANALYSIS OF THIN-LAYER CHROMATOGRAPHY PLATES BY NEAR-INFRARED FT-RAMAN

The qualitative analysis of small amounts of chemical compounds, after chromatographic separation on TLC plates is discussed. A brief summary is presented of published work using FTIR techniques. An initial study into the use and benefits of a near-IR FT-Raman instrument for this application is presented. Spectra using this technique were recorded directly from the TLC plates with no need for special treatment of the samples or the plates. FT-Raman spectral libraries are discussed and different search algorithms are compared for picking the TLC plate data from a medium sized FT-Raman library.