SPORULATION IN PHYSARUM POLYCEPHALUM - A MODEL SYSTEM FOR STUDIES ON DIFFERENTIATION

被引:54
作者
SAUER, HW
BABCOCK, KL
RUSCH, HP
机构
[1] McArdle Laboratory for Cancer Research, University of Wisconsin Medical Center, Madison
关键词
D O I
10.1016/0014-4827(69)90156-6
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The sporulating plasmodium of the slime mold Physarum polycephalum is an excellent system for studies on differentiation. Ample material maintained in axenic culture is available for biochemical studies; the changes are synchronous, distinct, and separate from growth; and the process may be easily initiated by starving a plasmodium and then exposing it to light. Studies reveal that sporulation is dependent on the synthesis of DNA prior to the period of illumination, on the continued synthesis of protein throughout the entire period, and on the synthesis of RNA until approx. 3 h after the end of the illumination period. Three hours after light exposure also marks the time at which processes associated with the early stages of sporulation attain a point of no return-a time at which the plasmodium is irreversibly committed to sporulate even though it is returned to a growth medium. © 1969.
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页码:319 / &
相关论文
共 29 条
[1]   SEQUENTIAL TEMPORAL REPLICATION OF DNA IN PHYSARUM POLYCEPHALUM [J].
BRAUN, R ;
MITTERMAYER, C ;
RUSCH, HP .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1965, 53 (05) :924-+
[2]   EFFECT OF ELEVATED TEMPERATURE SHOCKS ON MITOSIS AND ON INITIATION OF DNA REPLICATION IN PHYSARUM POLYCEPHALUM [J].
BREWER, EN ;
RUSCH, HP .
EXPERIMENTAL CELL RESEARCH, 1968, 49 (01) :79-&
[4]  
CERIOTTI GIOVANNI, 1955, JOUR BIOL CHEM, V214, P59
[5]   EFFECT OF ACTIDIONE ON MITOSIS IN SLIME MOLD PHYSARUM POLYCEPHALUM [J].
CUMMINS, JE ;
BREWER, EN ;
RUSCH, HP .
JOURNAL OF CELL BIOLOGY, 1965, 27 (02) :337-+
[6]  
Daniel J. W., 1964, METHOD CELL PHYSIOL, P9
[7]   METHOD FOR INDUCING SPORULATION OF PURE CULTURES OF MYXOMYCETE PHYSARUM POLYCEPHALUM [J].
DANIEL, JW ;
RUSCH, HP .
JOURNAL OF BACTERIOLOGY, 1962, 83 (02) :234-&
[8]  
DANIEL JW, 1966, CELL SYNCHRONY, P117
[9]   MORPHOGENESIS IN TRICHODERMA - PHOTOINDUCTION AND RNA [J].
GRESSEL, J ;
GALUN, E .
DEVELOPMENTAL BIOLOGY, 1967, 15 (06) :575-&
[10]   BIOCHEMISTRY OF DIFFERENTIATION [J].
GROSS, PR .
ANNUAL REVIEW OF BIOCHEMISTRY, 1968, 37 :631-+