STRUCTURE-ACTIVITY RELATIONSHIPS OF ONE-RING PSYCHOTOMIMETICS

被引：262

作者：

SHULGIN, AT

SARGENT, T

NARANJO, C

机构：

[1] Lafayette, CA

[2] Centro de Estudios de Antropologia Medica, Universidad de Chile, Santiago

来源：

NATURE | 1969年 / 221卷 / 5180期

关键词：

D O I：

10.1038/221537a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Human dose-response relationships for psychotomimetic phenethylamines:an isopropylamine side chain and triple methoxy substitution provide optimum activity. Available data suggest possible structures for the hypothetical psychotogen of schizophrenia. © 1969 Nature Publishing Group.

引用

页码：537 / &

共 37 条

[1] ABRAHAMSON HA, 1959, NEUROPHARMACOLOGY ED
[2] Alles GA, 1933, J PHARMACOL EXP THER, V47, P339
[3] ALLES GA, 1959, NEUROPHARMACOLOGY
[4] MESCALINE ANALOGS .3. 2,4,6-TRIALKYL AND 3,4-DIHYDROXY-5-METHOXY-BETA-PHENETHYLAMINES
BENINGTON, F
MORIN, RD
CLARK, LC
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1955, 20 (09) : 1292 - 1296
[5] CARLSSON A, 1964, PROGRESS BRAIN RESEA, V8
[6] A POSSIBLE CORRELATION BETWEEN DRUG-INDUCED HALLUCINATIONS IN MAN AND A BEHAVIOURAL RESPONSE IN MICE
CORNE, SJ
PICKERIN.W
[J]. PSYCHOPHARMACOLOGIA, 1967, 11 (01): : 65 - 65
[7] IDENTIFICATION OF 3,4-DIMETHOXYPHENETHYLAMINE FROM SCHIZOPHRENIC URIN BY MASS SPECTROMETRY
CREVELING, CR
DALY, JW
[J]. NATURE, 1967, 216 (5111) : 190 - +
[8] CHEMICAL AND ENZYMATIC ROUTES TO METHOXYDOPAMINES
DALY, J
WITKOP, B
HORNER, L
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1961, 83 (23) : 4787 - &
[9] DALY JW, 1960, J BIOL CHEM, V235, P1155
[10] EVIDENCE OF CATECHOLAMINE MEDIATION IN ABERRANT BEHAVIOUR INDUCED BY LYSERGIC ACID DIETHYLAMIDE (LSD) IN RAT
DIXON, AK
[J]. EXPERIENTIA, 1968, 24 (07): : 743 - &

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