DETERMINATION OF INDIVIDUAL UBIQUINONE HOMOLOGS BY MASS-SPECTROMETRY AND HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：27

作者：

IMABAYASHI, S

NAKAMURA, T

SAWA, Y

HASEGAWA, J

SAKAGUCHI, K

FUJITA, T

MORI, Y

KAWABE, K

机构：

[1] Eisai Research Laboratories, Eisai Co., Ltd., Bunkyo-ku, Tokyo 112

来源：

ANALYTICAL CHEMISTRY | 1979年 / 51卷 / 04期

关键词：

D O I：

10.1021/ac50040a019

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Ubiquinone homologues in various animal tissues (liver, kidney, heart, spleen) were determined by direct inlet selected ion monitoring. Samples were prepared by solvent extraction, after treating with lipase to eliminate substances that might interfere with the analysis. The detection limit by direct inlet selected ion monitoring for ubiquinone-10 was 0.1 ng. The same samples were also subjected to high performance liquid chromatography and results of this latter analysis were in good agreement with results by direct inlet selected ion monitoring. © 1979, American Chemical Society. All rights reserved.

引用

页码：534 / 536

页数：3

共 17 条

[1] ESTIMATION OF INDIVIDUAL COENZYME-Q HOMOLOGS IN A COENZYME-Q MIXTURE BY DENSITOMETRY
CASEY, AC
LEE, A
MYERS, P
[J]. JOURNAL OF CHROMATOGRAPHY, 1972, 72 (02): : 365 - +
[2] CRANE F. L., 1971, Methods in Enzymology, V18C, P137, DOI 10.1016/S0076-6879(71)18022-6
[3] ENZYME TOPOLOGY OF INTRACELLULAR MEMBRANES
DEPIERRE, JW
ERNSTER, L
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1977, 46 : 201 - 262
[4] UBIQUINONE CONTENT OF ANIMAL TISSUES - A SURVEY OF OCCURRENCE OF UBIQUINONE IN VERTEBRATES
DIPLOCK, AT
HASLEWOOD, GA
[J]. BIOCHEMICAL JOURNAL, 1967, 104 (03) : 1004 - +
[5] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF UBIQUINONES, FICAPRENOLS AND DOLICHOLS
DONNAHEY, PL
HEMMING, FW
[J]. BIOCHEMICAL SOCIETY TRANSACTIONS, 1975, 3 (05) : 775 - 776
[6] Green J., 1965, BIOCH QUINONES, P261
[7] NOVEL PEAK MATCHING TECHNIQUE BY MEANS OF A NEW AND COMBINED MULTIPLE ION DETECTOR-PEAK MATCHER DEVICE - ELEMENTAL ANALYSES OF COMPOUNDS IN SUBMICROGRAM QUANTITIES WITHOUT PRIOR ISOLATION
HAMMAR, CG
HESSLING, R
[J]. ANALYTICAL CHEMISTRY, 1971, 43 (03) : 298 - &
[8] LITTARRU GP, 1972, INT J VITAM NUTR RES, V42, P413
[9] UBIQUINONE AND RELATED COMPOUNDS .21. DETERMINATION OF UBIQUINONE-10 IN HUMAN BLOOD
MORIMOTO, H
IMADA, I
AMANO, T
TOYODA, M
ASHIDA, Y
[J]. BIOCHEMICAL MEDICINE, 1973, 7 (01): : 169 - 177
[10] NAKAMURA R, 1973, INT J VITAM NUTR RES, V43, P526

← 1 2 →