CHOICE OF ANESTHETIC AGENTS FOR PERIBULBAR ANESTHESIA

被引:18
作者
HOUSE, PH [1 ]
HOLLANDS, RH [1 ]
SCHULZER, M [1 ]
机构
[1] UNIV BRITISH COLUMBIA,UNIV HOSP,DEPT OPHTHALMOL,SITE 2211 WESBROOK MALL,VANCOUVER V6T 2B5,BC,CANADA
关键词
BUPIVACAINE; HYALURONIDASE; LIDOCAINE; LOCAL ANESTHESIA; PERIBULBAR ANESTHESIA;
D O I
10.1016/S0886-3350(13)80989-3
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
To determine the effectiveness of various combinations of lidocaine, epinephrine, and hyaluronidase with bupivacaine, a prospective, randomized, masked study on 117 patients having cataract extraction under local anesthesia was undertaken. All patients were given a 9 ml peribulbar block by one surgeon, and a graded assessment of analgesia and akinesia was made in a masked fashion one hour later. A mixture using all these agents gave significantly better results than any of the combinations (P = .001). No single agent was shown to be the major determinant of effectiveness. The result suggests a synergistic effect found only when all the agents are combined.
引用
收藏
页码:80 / 83
页数:4
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