NPE-RESIN, A NEW APPROACH TO THE SOLID-PHASE SYNTHESIS OF PROTECTED PEPTIDES AND OLIGONUCLEOTIDES .2. SYNTHESIS OF PROTECTED PEPTIDES

被引：20

作者：

ALBERICIO, F

GIRALT, E

ERITJA, R

机构：

[1] CSIC,CID,DEPT MOLEC GENET,JORDI GIRONA 18-26,E-08034 BARCELONA,SPAIN

[2] UNIV BARCELONA,DEPT ORGAN CHEM,E-08028 BARCELONA,SPAIN

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 11期

关键词：

D O I：

10.1016/0040-4039(91)80372-D

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of a polymer support containing the base-labile 2-(2-nitrophenyl)ethyl (NPE) handle allows the preparation of fully protected (Boc/Bzl) peptides, which may be used for the Convergent Solid-Phase Peptide Synthesis of large peptides or proteins.

引用

页码：1515 / 1518

页数：4

共 41 条

[1] CONVERGENT SOLID-PHASE PEPTIDE-SYNTHESIS .5. SYNTHESIS OF THE 1-4, 32-34, AND 53-59 PROTECTED SEGMENTS OF THE TOXIN-II OF ANDROCTONUS AUSTRALIS HECTOR [J].