WHOLE-BLOOD DEPROTEINIZATION FOR DRUG SCREENING USING AUTOMATIC PIPETTORS

被引：10

作者：

COLLINS, C ^{[1
]}

MUTO, J ^{[1
]}

SPIEHLER, V ^{[1
]}

机构：

[1] DIAGNOST PROD CORP,LOS ANGELES,CA 90045

来源：

JOURNAL OF ANALYTICAL TOXICOLOGY | 1992年 / 16卷 / 05期

关键词：

D O I：

10.1093/jat/16.5.340

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Automating the initial screening of postmortem blood and other tissues for drugs of abuse requires a pipetting procedure that is compatible with immunoassay screening tests. The deproteinization procedure uses a zinc sulfate-5-suifosalicylic acid reagent to precipitate blood proteins. This procedure for deproteinization of whole blood and tissue homogenates Is compatible with coated tube radioimmunoassays (RIA) and can therefore be used in automating the initial screening step. © 1992, Oxford University Press. All rights reserved.

引用

页码：340 / 342

页数：3

共 4 条

[1] EVALUATION OF THE RELATIVE EFFICACY OF VARIOUS TECHNIQUES FOR DEPROTEINIZING PLASMA SAMPLES PRIOR TO HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS
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[2] CHEN XH, IN PRESS J ANAL TOXI
[3] SAMPLE PREPARATION FOR BIOMEDICAL ANALYSIS
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[4] PRELIMINARY EVALUATION OF THE ABBOTT TDX FOR SCREENING OF D-METHAMPHETAMINE IN WHOLE-BLOOD SPECIMENS
SIMONICK, TF
WATTS, VW
[J]. JOURNAL OF ANALYTICAL TOXICOLOGY, 1992, 16 (02) : 115 - 118

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