LEVELS OF IGM ANTIBODIES AGAINST DENGUE VIRUS IN RIO-DE-JANEIRO, BRAZIL

被引:36
作者
NOGUEIRA, RMR
MIAGOSTOVICH, MP
CAVALCANTI, SMB
MARZOCHI, KBF
SCHATZMAYR, HG
机构
[1] ESCOLA NACL SAUDE PUBLICA,DEPT CIENCIAS BIOL,RIO JANEIRO,BRAZIL
[2] UNIV FED FLUMINENSE,DEPT VIROL,RIO JANEIRO,BRAZIL
来源
RESEARCH IN VIROLOGY | 1992年 / 143卷 / 06期
关键词
DENGUE; IGM; MAC-ELISA; PERSISTENCE; VIRUS TYPE-1; RIO-DE-JANEIRO;
D O I
10.1016/S0923-2516(06)80136-6
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The appearance and persistence of IgM antibodies were studied by MAC-ELISA in 926 confirmed cases of dengue virus type 1 infection. Assays performed on acute and convalescent patient sera revealed that IgM antibodies appeared during the early phase of disease (day 2) and persisted for three months after onset. MAC-ELISA proved to be a valuable early diagnosis test when compared with haemagglutination inhibition.
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页码:423 / 427
页数:5
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