PROTON MAGNETIC-RESONANCE SPECTROSCOPIC IMAGING IN PATIENTS WITH FRONTAL-LOBE EPILEPSY

被引：48

作者：

GARCIA, PA

LAXER, KD

VANDERGROND, J

HUGG, JW

MATSON, GB

WEINER, MW

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT RADIOL,SAN FRANCISCO,CA 94143

[2] UNIV CALIF SAN FRANCISCO,DEPT PHARMACEUT CHEM,SAN FRANCISCO,CA 94143

[3] UNIV CALIF SAN FRANCISCO,DEPT MED,SAN FRANCISCO,CA 94143

[4] UNIV ALABAMA,DEPT NEUROL,BIRMINGHAM,AL

来源：

ANNALS OF NEUROLOGY | 1995年 / 37卷 / 02期

关键词：

D O I：

10.1002/ana.410370222

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Proton magnetic resonance spectroscopic imaging (H-1 MRSI) has demonstrated decreased N-acetyl compounds (NA) in the epileptogenic hippocampus in patients with temporal lobe epilepsy. We studied 8 patients with frontal lobe epilepsy and found mean NA/creatine (Cr) in the epileptogenic frontal lobe decreased by 27% compared with that of the contralateral homologous region (1.81 +/- 0.36 vs 2.49 +/- 0.60, p < 0.008). In every patient, NA/Cr was decreased in the epileptogenic region by at least 5%. These findings suggest that H-1 MRSI may be useful in the presurgical evaluation of patients with frontal lobe epilepsy.

引用

页码：279 / 281

页数：3

共 15 条

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Abou-Kahlil Bassel, 1993, Epilepsia, V34, P121

[2]

Arnold D L, 1990, NMR Biomed, V3, P184, DOI 10.1002/nbm.1940030407

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