REGIOSPECIFIC BROMINATION OF 3-METHYLINDOLES WITH N-BROMOSUCCINIMIDE

被引：41

作者：

ZHANG, PW ^{[1
]}

LIU, RY ^{[1
]}

COOK, JM ^{[1
]}

机构：

[1] UNIV WISCONSIN,DEPT CHEM,MILWAUKEE,WI 53211

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 18期

关键词：

D O I：

10.1016/0040-4039(95)00478-U

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The regiospecific bromination of various substituted 3-methylindoles at either C(2) or the C(3) alkyl moiety was accomplished via an electrophilic or free radical bromination process to provide intermediates for indole alkaloid total synthesis. The regiospecificity of the bromination could be controlled by variation of both the substituent and the N(1) protecting group on the indole ring.

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页码：3103 / 3106

页数：4

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