REACTION OF ARYL AND ALKYL NITRO-COMPOUNDS WITH 2-BUTENYLMAGNESIUM CHLORIDE - SYNTHESIS OF A NEW CLASS OF NITRONES

Nitrones have received great attention during recent years because they have been revealed as important intermediates in organic synthesis. Indeed nitrones are versatile 1,3-dipoles useful for the construction of nitrogen heterocycles, which are largely present in natural products like alkaloids and β-lactams.1Some of them, e.g. phe-nyl-tert-butylnitrone have also been used as spin-trapping reagents and utilized in studies concerning radical. © 1990, American Chemical Society. All rights reserved.