SYNDROME RESEMBLING PROGRESSIVE SYSTEMIC-SCLEROSIS AFTER BONE-MARROW TRANSPLANTATION - MODEL FOR SCLERODERMA

被引：124

作者：

FURST, DE ^{[1
]}

CLEMENTS, PJ ^{[1
]}

GRAZE, P ^{[1
]}

GALE, R ^{[1
]}

ROBERTS, N ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT MED,LOS ANGELES,CA 90024

来源：

ARTHRITIS AND RHEUMATISM | 1979年 / 22卷 / 08期

关键词：

D O I：

10.1002/art.1780220815

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Six long term survivors of bone marrow transplants developed a syndrome similar to progressive systemic sclerosis (PSS). Cutaneous involvement (6/6), pulmonary disease (6/6), musculoskeletal involvement (4/6), keratoconjunctivitis/positive Schirmer's test (4/6), Raynaud's phenomenon (2/6), and renal and cardiac disease (1/6) were similar to findings in PSS patients. T and B lymphocyte counts and functions were also similar. This PSS‐like syndrome, including visceral involvement, after bone marrow transplantation lends support to an immunologic hypothesis of the pathogenesis of progressive systemic sclerosis. Copyright © 1979 American College of Rheumatology

引用

页码：904 / 910

页数：7

共 18 条

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