HIGHLY EFFICIENT AND GENERAL-METHOD FOR SYNTHESIS OF TERTIARY ALLYLIC ALCOHOLS IN A CHIRAL FORM - SYNTHESIS OF ARBAPROSTIL

被引：23

作者：

OKAMOTO, S ^{[1
]}

YOSHINO, T ^{[1
]}

TSUJIYAMA, H ^{[1
]}

SATO, F ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,DEPT BIOMOLEC ENGN,MEGURO KU,TOKYO 152,JAPAN

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 41期

关键词：

OPTICALLY ACTIVE TERTIARY ALLYLIC ALCOHOL; PETERSON OLEFINATION REACTION; PROSTAGLANDIN; ARBAPROSTIL;

D O I：

10.1016/S0040-4039(00)93557-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Highly efficient and general method for synthesis of optically active tertiary allylic alcohols (1) starting from readily available optically active gamma-trimethylsilyl-beta,gamma-epoxy tertiary alcohols (3), and the application of the reaction product to the synthesis of arbaprostil are described.

引用

页码：5793 / 5796

页数：4

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