DOSE-DEPENDENT SHIFTS IN THE SULFATION AND GLUCURONIDATION OF PHENOLIC-COMPOUNDS IN THE RAT INVIVO AND IN ISOLATED HEPATOCYTES - THE ROLE OF SATURATION OF PHENOLSULFOTRANSFERASE

被引：99

作者：

KOSTER, H

HALSEMA, I

SCHOLTENS, E

KNIPPERS, M

MULDER, GJ

机构：

来源：

BIOCHEMICAL PHARMACOLOGY | 1981年 / 30卷 / 18期

关键词：

D O I：

10.1016/0006-2952(81)90584-0

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：2569 / 2575

页数：7

共 27 条

[1]

ANDERSSON B, 1978, DRUG METAB DISPOS, V6, P611

[2] HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS - A BIOCHEMICAL AND FINE STRUCTURAL STUDY [J].

BERRY, MN ;

FRIEND, DS .

JOURNAL OF CELL BIOLOGY, 1969, 43 (03) :506-+

[3] KINETIC STUDIES OF THE METABOLISM OF FOREIGN ORGANIC COMPOUNDS .4. THE CONJUGATION OF PHENOLS WITH SULPHURIC ACID [J].

BRAY, HG ;

HUMPHRIS, BG ;

THORPE, WV ;

WHITE, K ;

WOOD, PB .

BIOCHEMICAL JOURNAL, 1952, 52 (04) :419-423

[4] FATE OC [C-14]PHENOL IN VARIOUS SPECIES [J].

CAPEL, ID ;

WILLIAMS, RT ;

SMITH, RL ;

MILLBURN, P ;

FRENCH, MR .

XENOBIOTICA, 1972, 2 (01) :25-&

[5] PHENOL CONJUGATION BY LUNG INVIVO [J].

CASSIDY, MK ;

HOUSTON, JB .

BIOCHEMICAL PHARMACOLOGY, 1980, 29 (03) :471-474

[6] INVIVO ASSESSMENT OF EXTRA-HEPATIC CONJUGATIVE METABOLISM IN 1ST PASS EFFECTS USING THE MODEL-COMPOUND PHENOL [J].

CASSIDY, MK ;

HOUSTON, JB .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1980, 32 (01) :57-59

[7]

CHENG S, 1980, J BIOL CHEM, V255, P2637

[8]

Dutton G. J. F., 1980, GLUCURONIDATION DRUG

[9] BIOTRANSFORMATION OF 4-DIMETHYLAMINOPHENOL IN ISOLATED PERFUSED RAT-LIVER AND IN RAT [J].

EYER, P ;

KAMPFFMEYER, HG .

BIOCHEMICAL PHARMACOLOGY, 1978, 27 (18) :2223-2228

[10]

Jakoby WB, 1980, ENZ BAS DET, V2, P63

← 1 2 3 →