HUMAN AND BOVINE DOPAMINE BETA-HYDROXYLASE ACTIVITY STUDIES

被引：3

作者：

BOHUON, C

GUERINOT, F

机构：

[1] Unité de Biologie Clinique et Expérimentale, Institut Gustave Roussy

来源：

CLINICA CHIMICA ACTA | 1968年 / 19卷 / 01期

关键词：

D O I：

10.1016/0009-8981(68)90197-6

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The kinetics of dopamine hydroxylase extracted from two human tumors (one pheochromocytoma and one neuroblastoma) are reported. Two substrates have been studied: dopamine (DM) and 3-methoxytyramine (3-MT). The activity of neuroblastoma enzyme on 3-MT is low and the hypothesis of a by-pass in the biosynthesis of noradrenaline (NA) is invalidated. Results with foetal bovine dopamine hydroxylase show no difference from those with bovine adult enzyme. © 1968.

引用

页码：125 / &