NEW BROAD-SPECTRUM AMINOGLYCOSIDE ANTIBIOTIC COMPLEX, SPORARICIN .1. FERMENTATION, ISOLATION AND CHARACTERIZATION

被引：40

作者：

DEUSHI, T

IWASAKI, A

KAIYA, K

KUNIEDA, T

MIZOGUCHI, T

NAKAYAMA, M

ITOH, H

MORI, T

ODA, T

机构：

[1] Tokyo Research Laboratories, Kowa Co., Ltd., Higashimurayama

来源：

JOURNAL OF ANTIBIOTICS | 1979年 / 32卷 / 03期

关键词：

D O I：

10.7164/antibiotics.32.173

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Two new aminoglycoside antibiotics, sporaricins A (C17H35N5O5) and B (C15H32N4O4) produced by a rare actinomycetales, Saccharopolyspora hirsuta subsp. kobensis have been isolated by column chromatography on a cation-exchange resin. Sporaricin A is highly active against Gram-positive and Gram-negative bacteria including aminoglycoside-resistant strains. © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：173 / 179

页数：7

共 5 条

[1] NEW BROAD-SPECTRUM AMINOGLYCOSIDE ANTIBIOTIC COMPLEX, SPORARICIN .3. STRUCTURES OF SPORARICINS-A AND SPORAICINS-B [J].