ASTHMA - A DIAGNOSTIC AND THERAPEUTIC CHALLENGE

被引:9
作者
JONES, K
LANE, D
HOLGATE, ST
PRICE, J
机构
[1] Department of Primary Medical Care, University of Southampton
[2] Osler Chest Unit, Churchill Hospital, Oxford
[3] Department of Immunopharmacology, University of Southampton
[4] Department of Paediatric, Kings College Hospital, London
关键词
D O I
10.1093/fampra/8.1.97
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Asthma is a disease needing urgent action. Morbidity and mortality are rising,1,2 despite advances in our understanding of asthma3 and in its treatment.5,6 The lifetime prevalence of asthma in children varies from 5 to 31%, depending on the defining criteria, and even when recent prevalence (occurring in the past two years) is examined, rates from 5 to 18% have been found.7 There is growing evidence which shows that signs of reversible airways disease occur in the elderly with even greater frequency8,9 and it is likely that at least 10% of the population will need asthma treatment at some stage of their lives: this means that well over five million people in the UK or 250 patients in each 'average' general practice list of 2500 merit the diagnosis of asthma at some stage of their lives. The fact that an average practice is likely to have diagnosed less than half that number clearly implies that asthma is first and foremost an underdiagnosed disease.
引用
收藏
页码:97 / 99
页数:3
相关论文
共 28 条
[1]  
Burney P.G.J., Asthma mortality in England and Wales: Evidence for a further increase, Lancet, 2, pp. 323-326, (1986)
[2]  
Fleming D.M., Crombie D.L., Prevalence of asthma and hay fever in England and Wales, Br Med J, 294, pp. 279-283, (1987)
[3]  
Holgate S.T., Finnerty J.P., Recent advances in understanding the pathogenesis of asthma and its clinical implications, Q J Med, 66, pp. 5-19, (1988)
[4]  
Cookson W., Hopkin J.M., Dominant inheritance of atopic immunoglobulin E responsiveness, Lancet, 1, pp. 86-88, (1988)
[5]  
Keating G., Etal. Trends in sales of drugs for asthma in New Zealand, Australia and the United Kingdom, Br Med J, 289, pp. 348-351, (1984)
[6]  
Hay 1 F.C., Higenbottam T.W., Has the management of asthma improved?, Lancet, 2, pp. 609-611, (1987)
[7]  
Usherwood T.P., Factors affecting estimates of the prevalence of asthma and wheezing in childhood, Family Pract, 4, pp. 318-321, (1987)
[8]  
Banerjee D.K., Lee G.S., Malik S.K., Daly S., Underdiagnosis asthma in the elderly, Br J Dis Chest, 81, pp. 23-29, (1987)
[9]  
Holgate S.T., Dow L., Airways disease in the elderly: An easy to miss diagnosis, J Resp Dis, 9, pp. 14-22, (1988)
[10]  
Speight A.N.P., Is childhood asthma being underdiagnosed and undertreated?, Br Med J, 2, pp. 331-332, (1978)