REMOTE AROMATIC METALATION - AN ANIONIC FRIEDEL-CRAFTS EQUIVALENT FOR THE REGIOSELECTIVE SYNTHESIS OF CONDENSED FLUORENONES FROM BIARYL AND META-TERARYL 2-AMIDES

被引：91

作者：

FU, JM ^{[1
]}

ZHAO, BP ^{[1
]}

SHARP, MJ ^{[1
]}

SNIECKUS, V ^{[1
]}

机构：

[1] UNIV WATERLOO,GUELPH WATERLOO CTR GRAD WORK CHEM,WATERLOO N2L 3G1,ONTARIO,CANADA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 05期

关键词：

D O I：

10.1021/jo00005a004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Remote metalation (t-BuLi, LDA) of m-teraryl and biaryl amides (Scheme I) constitutes a short and convenient route to a variety of substituted and condensed fluorenones, including aza analogues (Table I) and the natural product, dengibsinin (6a, Scheme II).

引用

页码：1683 / 1685

页数：3

共 28 条

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