REGULATION OF INFLAMMATION BY LIPOCORTIN-1

被引：67

作者：

GOULDING, NJ ^{[1
]}

GUYRE, PM ^{[1
]}

机构：

[1] DARTMOUTH COLL, HITCHCOCK MED CTR, DARTMOUTH MED SCH, DEPT PHYSIOL, HANOVER, NH 03756 USA

来源：

IMMUNOLOGY TODAY | 1992年 / 13卷 / 08期

关键词：

D O I：

10.1016/0167-5699(92)90040-E

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The mechanisms that regulate inflammatory responses, and their dysfunction in chronic inflammatory diseases, are poorly understood. Lipocortin 1 is a potential mediator of the anti-inflammatory effects of glucocorticoid hormones. Following the discovery of Putative receptors on phagocytes for lipocortin 1, Nick Goulding and Paul Guyre here offer one explanation for the self-limitation of inflammation and the impairment of the mechanism in chronic inflammatory disease.

引用

页码：295 / 297

页数：3

共 38 条

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