PRECOCIOUS PUBERTY - AUXOLOGICAL CRITERIA DISCRIMINATING DIFFERENT FORMS

被引：4

作者：

BASSI, F ^{[1
]}

BARTOLINI, O ^{[1
]}

NERI, AS ^{[1
]}

GHERI, RG ^{[1
]}

BUCCIANTINI, S ^{[1
]}

CHELI, D ^{[1
]}

BRUNI, V ^{[1
]}

机构：

[1] USL 10D, DIV RADIOL, FLORENCE, ITALY

来源：

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION | 1994年 / 17卷 / 10期

关键词：

PRECOCIOUS PUBERTY; LH-RH ANALOGS; PREDICTED HEIGHT; BONE AGE;

D O I：

10.1007/BF03347778

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

It may be possible to recognize different forms of precocious puberty at the first evaluation. In a group of 26 sexually precocious girls we used Bayley-Pinneau predicted adult height (P.A.H.) to discriminate patients with 'poor' or 'good' height prognosis. Patients with evidence of impaired height prognosis (P.A.H. <-1 SDS) (Group 1)were immediately treated with LH-RH analogs, while patients with unimpaired height prognosis (P.A.H. >-1 SDS) (Group 2) were followed without therapy. Two yr of treatment significantly improved P.A.H. in Group 1 patients, from a mean of -1.68+/-0.4 to a mean of -0.57+/-0.6 (SDS) (p<0.01). After the 2 yr observation period, Group 2 patients showed no significant variation of P.A.H. (from a mean of 0.45+/-0.8 to a mean of 0.33+/-0.6). The retrospective analysis of the growth pattern changes in the two Groups seems to indicate that LH-RH agonist treatment improves height potential in girls with initial poor height prognosis and that girls with initial good height prognosis maintain an unimpaired growth potential.

引用

页码：793 / 797

页数：5

共 27 条

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