AN IMPROVED SYNTHESIS OF 2',3'-DIDEOXYCYTIDINE

被引：5

作者：

BHAT, V

UGARKAR, BG

GRIMM, K

STOCKER, E

DOMENICO, PA

SAYEED, VA

KOSORA, N

机构：

[1] Pharm-Eco Laboratories Inc., Simi Valley, CA 93065

来源：

NUCLEOSIDES & NUCLEOTIDES | 1990年 / 9卷 / 08期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1080/07328319008046062

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A convenient synthesis of 2',3'-dideoxycytidine (ddC, 6) from 2'-deoxycytidine (1) has been achieved employing a base-catalyzed elimination of 3'-O-methanesulfonyl group as the key step.

引用

页码：1061 / 1065

页数：5

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