SYNTHESIS OF (3R,5S,6R)-2,6-DIACETOXYMETHYLCLAVAM FROM D-GALACTAL

被引：15

作者：

CHMIELEWSKI, M

GRODNER, J

机构：

[1] Institute of Organic Chemistry, Polish Academy of Sciences

来源：

JOURNAL OF CARBOHYDRATE CHEMISTRY | 1992年 / 11卷 / 06期

关键词：

D O I：

10.1080/07328309208020086

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

N- (t-Butyl)dimethylsilyl-2-C:l-N-carbonyl-2-deoxy-alpha-D-galactopyranosylamine (1) was tritylated and the product was subjected to a glycolic cleavage to give dialdehyde 10. Subsequently, compound 10 was transformed into bromide 14 using standard procedures. The fluoride anion induced cyclization in 14 afforded clavam 15.

引用

页码：691 / 698

页数：8

共 15 条

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