SYNTHESIS OF (R)-LYSOTHIOPHOSPHATIDIC ACID AND (R)-THIOPHOSPHATIDIC ACID

被引：8

作者：

HEEB, NV ^{[1
]}

NAMBIAR, KP ^{[1
]}

机构：

[1] UNIV CALIF DAVIS,DEPT CHEM,DAVIS,CA 95616

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 39期

关键词：

D O I：

10.1016/S0040-4039(00)73707-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(R)-Thiophosphatidic acid and (R)-lysothiophosphatidic acid were obtained in an efficient synthesis from a chiral glycerol precursor via sulfurization of a bis(2-cyanoethyl) phosphite triester.

引用

页码：6193 / 6196

页数：4

共 15 条

[1] INTERACTIONS OF THIOPHOSPHATIDIC ACID WITH ENZYMES WHICH METABOLIZE PHOSPHATIDIC-ACID - INHIBITION OF PHOSPHATIDIC-ACID PHOSPHATASE AND UTILIZATION BY CDP-DIACYLGLYCEROL SYNTHASE [J].

BONNEL, SI ;

LIN, YP ;

KELLEY, MJ ;

CARMAN, GM ;

EICHBERG, J .

BIOCHIMICA ET BIOPHYSICA ACTA, 1989, 1005 (03) :289-295

[2] ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETIC ACID, A VERSATILE REAGENT FOR DETERMINATION OF ENANTIOMERIC COMPOSITION OF ALCOHOLS AND AMINES [J].

DALE, JA ;

DULL, DL ;

MOSHER, HS .

JOURNAL OF ORGANIC CHEMISTRY, 1969, 34 (09) :2543-&

[3] AN EFFICIENT METHOD FOR THE PARTIAL SYNTHESIS OF MIXED-CHAIN PHOSPHATIDYLETHANOLAMINES [J].

DELFINO, JM ;

SCHREIBER, SL ;

RICHARDS, FM .

TETRAHEDRON LETTERS, 1987, 28 (21) :2327-2330

[4] NUCLEOSIDE PHOSPHOROTHIOATES [J].

ECKSTEIN, F .

ANNUAL REVIEW OF BIOCHEMISTRY, 1985, 54 :367-402

[5] PHOSPHATIDIC-ACID AND LYSOPHOSPHATIDIC ACID STIMULATE RECEPTOR-REGULATED MEMBRANE CURRENTS IN THE XENOPUS-LAEVIS OOCYTE [J].

FERGUSON, JE ;

HANLEY, MR .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1992, 297 (02) :388-392

[6]

JALINK K, 1990, J BIOL CHEM, V265, P12232

[7] ENZYMES IN ORGANIC-SYNTHESIS [J].

JONES, JB .

TETRAHEDRON, 1986, 42 (13) :3351-3403

[8] THE MITOGENIC ACTIVITIES OF PHOSPHATIDATE ARE ACYL-CHAIN-LENGTH DEPENDENT AND CALCIUM INDEPENDENT IN C3H/10T1/2 CELLS [J].

KRABAK, MJ ;

HUI, SW .

CELL REGULATION, 1991, 2 (01) :57-64

[9] APPLICATION OF 2-CYANOETHYL N,N,N',N'-TETRAISOPROPYLPHOSPHORODIAMIDITE FOR INSITU PREPARATION OF DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE IN POLYMER-SUPPORTED SYNTHESIS OF OLIGODEOXYRIBONUCLEOTIDES [J].

NIELSEN, J ;

TAAGAARD, M ;

MARUGG, JE ;

VANBOOM, JH ;

DAHL, O .

NUCLEIC ACIDS RESEARCH, 1986, 14 (18) :7391-7403

[10]

NIELSEN J, 1986, J CHEM RES, V26, P26

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