学术探索
学术期刊
新闻热点
数据分析
智能评审

SYNTHESIS AND ANTIHYPERTENSIVE ACTIVITY OF A SERIES OF 8-SUBSTITUTED 1-OXA-3,8-DIAZASPIRO[4.5]DECAN-2-ONES

被引：24
作者：
CAROON, JM
CLARK, RD
KLUGE, AF
NELSON, JT
STROSBERG, AM
UNGER, SH
MICHEL, AD
WHITING, RL
机构：
[1] SYNTEX RES CORP,INST ORGAN CHEM,PALO ALTO,CA 94304
[2] SYNTEX RES CORP,INST PHARMACOL & METAB,PALO ALTO,CA 94304
[3] SYNTEX RES CTR,EDINBURGH,SCOTLAND
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1981年 / 24卷 / 11期
关键词：
D O I：
10.1021/jm00143a012
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：1320 / 1328
页数：9
相关论文
共 34 条
  • [1] MODIFICATION BY ANTIHYPERTENSIVE DRUGS OF REFLEX CIRCULATORY RESPONSES INDUCED BY VERTICAL TILTING OR BILATERAL CAROTID OCCLUSION
    ANTONACCIO, MJ
    ROBSON, RD
    POVALSKI, HS
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1973, 22 (01) : 23 - 31
  • [2] ANTIHYPERTENSIVE UREIDOPIPERIDINES
    ARCHIBALD, JL
    BEARDSLEY, DR
    BISSET, GMF
    FAIRBROTHER, P
    JACKSON, JL
    OPALKO, A
    WARD, TJ
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (08) : 857 - 861
  • [3] SYNTHESIS AND HYPOTENSIVE ACTIVITY OF BENZAMIDOPIPERIDYLETHYLINDOLES
    ARCHIBALD, JL
    ALPS, BJ
    CAVALLA, JF
    JACKSON, JL
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (11) : 1054 - +
  • [4] SOME QUANTITATIVE USES OF DRUG ANTAGONISTS
    ARUNLAKSHANA, O
    SCHILD, HO
    [J]. BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1959, 14 (01): : 48 - 58
  • [5] Baer E, 1939, J BIOL CHEM, V128, P463
  • [6] SYMBIOTIC APPROACH TO DRUG DESIGN - ANTIHYPERTENSIVE BETA-ADRENERGIC BLOCKING-AGENTS
    BALDWIN, JJ
    LUMMA, WC
    LUNDELL, GF
    PONTICELLO, GS
    RAAB, AW
    ENGELHARDT, EL
    HIRSCHMANN, R
    SWEET, CS
    SCRIABINE, A
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (11) : 1284 - 1290
  • [7] SYNTHESIS OF(R)-EPICHLOROHYDRIN AND (S)-EPICHLOROHYDRIN
    BALDWIN, JJ
    RAAB, AW
    MENSLER, K
    ARISON, BH
    MCCLURE, DE
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1978, 43 (25) : 4876 - 4878
  • [8] FUNCTIONAL BASIS FOR CLASSIFICATION OF ALPHA-ADRENERGIC RECEPTORS
    BERTHELSEN, S
    PETTINGER, WA
    [J]. LIFE SCIENCES, 1977, 21 (05) : 595 - 606
  • [9] BRITTAIN RT, 1976, BRIT J CLIN PHARMACO, V3, P681
  • [10] EFFECTS OF ALPHA-ADRENOCEPTOR AGONISTS AND ANTAGONISTS ON RESPONSES OF TRANSMURALLY STIMULATED PROSTATIC AND EPIDIDYMAL PORTIONS OF THE ISOLATED VAS-DEFERENS OF THE RAT
    BROWN, CM
    MCGRATH, JC
    SUMMERS, RJ
    [J]. BRITISH JOURNAL OF PHARMACOLOGY, 1979, 66 (04) : 553 - 564
1234